Medical Disclaimer
The medications listed on this website are provided for informational purposes only. Their inclusion does not guarantee that they will be prescribed to any individual, as treatment decisions are ultimately at the discretion of healthcare providers. This list is not exhaustive, and healthcare providers may prescribe other medications, including non-stimulant options, based on the patient's unique health circumstances and needs.

ADHD patients often have trouble controlling their emotions and impulsive behaviors.

This is because the brain is wired differently and has less white matter compared to normal individuals.

As a result, they fail to process information correctly and have trouble concentrating on tasks. 

Even with the ugly symptoms, treating ADHD isn’t as complicated as most people think. As a matter of fact, the eventual solution starts from managing the root causes effectively.

Get your ADHD symptoms under control- Click the button below to book your appointment.

With proper usage of effective drugs like Vyvanse, there is a high probability that ADHD can become a thing of the past. 

But how long does Vyvanse last? Keep following as we divulge essential benefits and how long Vyvanse stays in your system.

What Is Vyvanse?

Vyvanse was first brought to market at the end of 2007 as a collaboration product between New River Pharmaceuticals and Shire BioChem.

What Is Vyvanse Used to Treat?

Well, Vyvanse also known as lisdexamfetamine dimesylate is a central nervous system stimulant used to treat attention deficit hyperactivity disorder. 

It is the first once-daily extended-release amphetamine product approved by the FDA for treating ADHD symptoms in adults and children beyond six years.

You can find the drug in different strengths of:

  • 5 mg
  • 10 mg
  • 20 mg
  • 30 mg
  • 40 mg
  • 50 mg 

How Long Does Vyvanse Last?

Like any other stimulant, Vyvanse causes a feeling of intense happiness or ecstasy when ingested in mega doses.

However, a proper dosage helps patients remain alert and focused throughout the day. It is worth noting that a misuse of the drug can result in adverse symptoms and overdependence. 

That said, there is a common question that medics face.

How Long Does It Take for 30 mg of Vyvanse to Wear Off?

It takes an average of 30 minutes for the half-life of Vyvanse to get eliminated from the body system. This estimate would take roughly 4 to 5 hours for the entire dose to clear completely.

 How Long Does Vyvanse Last

Vyvanse Duration In Urine, Blood, and Hair

Another common query you can come across is:

How Long Does Vyvanse Stay in Your Urine, Hair, and Blood?

Mainly, Vyvanse or the drug metabolites remain detectable in a human being blood eight hours after ingestion.

In urine samples, it is possible to detect Vyvanse up to three days later. Compared to all analyses, hair has the highest detection period that sometimes surpasses one month. However, it usually takes a couple of days for a hair sample to detect Vyvanse. 

Altogether, Do You Have a Clue on How to Make Vyvanse Last Longer?

Factors that influence how long does Vyvanse last:

  • Exercise

Regular body exercises help the brain to release dopamine and other neurotransmitters.

Given that ADHD patients have minimal dopamine, body activity enables them to think clearly and become more attentive. As a result, Vyvanse comes as an ideal boost to an already improved situation. 

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  • Proteins

An increased protein intake has an almost similar effect compared to Vyvanse boosting. In addition, the drug does not negatively impact Vvyanse outcome but rather augment its performance.

  • Vitamin C

Vitamin C slows down the body’s capability to break down Vyvanse into amphetamine. Bear in mind that although the drug lasts longer, the effect is slightly less. 

For How Many Hours Is Vyvanse Effective?

Since Vyvanse is a prodrug, take it orally for the body to metabolize and make it effective. When ingested, it takes 1-2 hours for the drug to become effective. Afterward, the sensation lasts approximately 8 to 14 hours in the patient’s body.

 Medics often refer to it as a smooth medication because there are no hiccups when the drug gets absorbed into the system. Furthermore, there is minimal rebound when the Vyvanse wears off compared to other medicines.


More impressive is that Vyvanse side effects are manageable and rarely detrimental to the user’s life.

Nonetheless, you should expect reactions like:

 How Long Does Vyvanse Last

Things to Avoid When Taking Vyvanse

Is Vyvanse Stronger Than Adderall?

Adderall and Vyvanse both contain amphetamines and function in an almost similar way. The only difference is that Adderall comprises four types of amphetamine salts compared to Vyvanse’s singular component known as lisdexamfetamine. 

On the other hand, Adderall amphetamine salts are:

  • Amphetamine sulfate
  • Amphetamine aspartate
  • Dextroamphetamine saccharate
  • Dextroamphetamine sulfate

Thanks to Vyvanse’s composition, the drug is less likely to get abused. This comes as an advantage in the battle against drugs dependence and inappropriate use. 

How Much Does Vyvanse Cost?

Unfortunately, there is no generic Vyvanse option available in the market. For instance, Adderall 100 capsules (5 mg) costs around $753. 

A generic version is slightly cheaper at around $58 to $176, depending on the vendor. Surprisingly, the same quantity of Vyvanse costs about $1170. Even if this figure is slightly overboard for most people, there is a high probability that experts may present a generic Vyvanse before the end of 2023.

Learn about the best treatment options for ADHD and get it treated by a licensed ADHD expert.

Final Thoughts

Undeniably, the primary source of concern with ADHD patients is how long does Vyvanse last?

You might realize that Vyvanse gives instant vigor and motivation soon after consumption. Yet, the positive effect does not last much.

The bottom line is to ensure that the drug improves:

  • Impulse control
  • Concentration
  • Focus

If your Vyvanse gives you nothing close to this, talk to verified mental health experts at EZCare Clinic for the best way forward.

Click the banner below to schedule your appointment. 

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Evidence Based

This article is based on scientific evidence, written by experts and fact checked by experts.

Our team of experts strive to be objective, unbiased, honest and to present both sides of the argument.

This article contains scientific references. The numbers
in the parentheses (1, 2, 3) are clickable links to peer-reviewed scientific papers.