Medical Disclaimer
The medications listed on this website are provided for informational purposes only. Their inclusion does not guarantee that they will be prescribed to any individual, as treatment decisions are ultimately at the discretion of healthcare providers. This list is not exhaustive, and healthcare providers may prescribe other medications, including non-stimulant options, based on the patient's unique health circumstances and needs.

In the modern mental health care system, Wellbutrin takes the forefront amongst the most preferred first-line antidepressants. Mainly, medics prescribe Wellbutrin for :

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Wellbutrin makes an ideal off-label treatment option for:

Basically, an off-label is a non-approved drug by the Food and Drug Administration to treat certain conditions. 

Before prescription, a qualified mental health expert thoroughly examines a patient’s symptoms to determine whether an off-label treatment is essential or not. 

Keep following as we define: How long does it take for Wellbutrin to work?

Also, we will take time to discuss: Does Wellbutrin make you feel happy?

How Long Does It Take to Feel the Effects of Wellbutrin?

Similar to other antidepressants, it might take about six weeks to observe significant changes in your symptoms. Nonetheless, you may notice slight improvements in your appetite, energy levels, and sleep patterns in the first or second week.

 It is worth noting that in the market, you may find Wellbutrin labeled as:

Furthermore, any form of Wellbutrin comes in:

  • Sustained-release (SR)
  • Immediate-release
  • Orally taken extended tablet (XL)

Typically, sustained-release drugs are designed to liberate the body at a predetermined pace to maintain a steady supply within a designated time.

On the other hand, although extended-release medications contain sustained-release they take slightly longer to move and absorb in the body. 

Wellbutrin Prescription

When Are Your Prescribed Wellbutrin?

How Long Does It Take for Wellbutrin XL and SR to Work?

Whether taking XL or SR, it usually takes about six to eight weeks for significant symptoms to subsidize. Typically, do you have an idea How it Works? 

The Wellbutrin effect starts by mildly blocking the nerve cells (neurons) from absorbing dopamine and norepinephrine neurotransmitters. 

In standard cases, these neurotransmitters are essential in regulating brain responses and moods. Overly, a proper Wellbutrin dosage increases neurotransmitters leading to reduced anxiety or depression symptoms.

Currently, Wellbutrin XL drugs come in:

  • 300 mg
  • 150 mg 

For SR medications, you can either find them in the following tablets:

  • 200 mg
  • 150 mg
  • 100 mg

Often it is not unusual to hear patients ask, How long does it take for Wellbutrin xl 300 mg to work? Since this is the highest Wellbutrin dosage, doctors only prescribe it in severe conditions.

Nonetheless, the absorption process in the body is almost similar to other quantities specified. 

How Does Wellbutrin Make You Feel?

Given that drug reaction differs from one person to another; individuals may experience a whole load of Wellbutrin side effects.

For example, soon after the first dosage, some patients complain of increased:

In this state of confusion, some patients may feel obliged to cut down on their dosage or stop entirely.

Unfortunately, this may escalate the situation further and make it complicated to treat.

As a result, contact your doctor immediately you notice some unusual reactions. 

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Frequently Asked Questions About Wellbutrin

Below are some of the most common questions that can help you make a clear decision about Wellbutrin uses.

  • Does Wellbutrin Make You Feel Happy?

As mentioned above, Wellbutrin triggers the performance of dopamine [1*] and norepinephrine.

Remember that these are feel-good neurotransmitters that trigger excitement in the body. For this reason, most medics prescribe it to offer a stimulant-like reaction without causing ugly side effects. 

  • Can Wellbutrin Make You Feel Crazy?

On rare occasions, some victims exhibit extreme agitation and restlessness. Sometimes, this is a reaction to the Wellbutrin dosage given. If a patient becomes excessively anxious soon after, consult your doctor right away.

  • Will Wellbutrin Give Me Energy?

Although Wellbutrin triggers excitement, studies indicate that the drug does not positively enhance energy levels. Instead, patients report increased relaxation, which helps them run their activities effectively and sleep much better. 


Wellbutrin Facts

  • How Long Does It Take for Wellbutrin to Work and Help Me to Focus?

Since Wellbutrin ensures dopamine and norepinephrine remain in the brain for longer durations, there is a higher possibility that it can help patients focus better. However, to enjoy such a positive reaction and minimize Wellbutrin side effects, patients need to follow their doctor’s instructions properly. 

  • How Long Should I Use Wellbutrin?

It is pretty tempting to quit on medication when an ailment gets better. However, with mental health, you need to be extra careful lest the symptoms come back. Therefore, take at least 6-9 months before completely getting off from depressants. 

  • How Wellbutrin Works for Anxiety?

Without any doubt, Wellbutrin is an effective remedy for anxiety and related conditions. Still, how and when should you take Bupropion for anxiety?

According to a recent case study, a minimal dose of 150 mg daily plays a significant role in minimizing anxiety symptoms and panic attacks. Luckily you can take Bupropion with or without food.

Importantly, store your drugs at room temperature and away from moisture and light.

In cases when you miss a single dose, take it the moment you remember. Even so, never take double dosages at the same time. Instead, take the next dosage four hours later. 

If you wish to stop your medication, consult your therapist on proper tapering to deter adverse withdrawals and Wellbutrin side effects.

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Last Word

Even if Wellbutrin causes minimal interactions, it is vital to inform your doctor if you suffer from other conditions. Moreover, alcohol and drug abuse sometimes increase the severity of side effects, leading to suicidal thoughts or severe seizures.

Above all, remember that how and when should you take Bupropion remains the backbone to quick and effective healing. For this reason, contact qualified mental health specialists at the EZCare Clinic for proper diagnosis and optimal treatment options. 


+1 sources
  1. A Review of the Neuropharmacology of Bupropion, a Dual Norepinephrine and Dopamine Reuptake Inhibitor. (2004)
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Evidence Based

This article is based on scientific evidence, written by experts and fact checked by experts.

Our team of experts strive to be objective, unbiased, honest and to present both sides of the argument.

This article contains scientific references. The numbers
in the parentheses (1, 2, 3) are clickable links to peer-reviewed scientific papers.