The medications listed on this website are provided for informational purposes only. Their inclusion does not guarantee that they will be prescribed to any individual, as treatment decisions are ultimately at the discretion of healthcare providers. This list is not exhaustive, and healthcare providers may prescribe other medications, including non-stimulant options, based on the patient's unique health circumstances and needs.
Do you feel an insignificant change from therapy or other non-drug treatments for depression? If so, it can indicate that you also need medication to feel better.
Antidepressants are frequently recommended as the first-line treatment against depression and anxiety, often in combination with therapy. However, the choice of treatment depends on various factors such as the severity of symptoms, medical history, and the patient’s needs. Therefore, it is important to consult with a healthcare provider to determine the best course of treatment for each individual.
Read on if you’re interested in learning more about these medications and how to get antidepressants prescribed.
Contact an expert and seek medical assistance if depression worsens your life.
Antidepressants: An Overview
Antidepressants are medications commonly used to treat depression, anxiety disorders, and other mental health illnesses. They work by affecting the levels of certain chemicals in the brain, such as serotonin, norepinephrine, and dopamine.
There are several different types of
- Selective serotonin reuptake inhibitors (SSRIs). They prevent serotonin from being removed from the brain (or reabsorbed), which causes an increase in serotonin levels. Serotonin is a hormone that helps regulate our mood and feelings, so having the proper balance is important. Commonly prescribed SSRIs include Prozac (fluoxetine), Zoloft (sertraline), Lexapro (escitalopram), and Celexa (citalopram).
- Serotonin-norepinephrine reuptake inhibitors (SNRIs). Similar to SSRIs, these medications prevent the breakdown of neurotransmitters. But, in addition to raising serotonin levels, SNRIs also raise norepinephrine, a neurotransmitter that promotes nerve cell communication and regulates the body’s response to stress, resulting in improved mood, concentration, and alertness. Examples of SNRIs include Cymbalta (duloxetine), Effexor (venlafaxine), and Pristiq (desvenlafaxine).
- Tricyclic antidepressants (TCAs). It is an older antidepressant class. These medications work to treat depression by preventing the breakdown of norepinephrine and serotonin. As a result of their potential for more serious adverse effects, they are less frequently prescribed than SSRIs and SNRIs. Common TCAs are Pamelor (nortriptyline) and Tofranil (imipramine).
- Monoamine oxidase inhibitors (MAOIs). MAOIs, one of the first developed antidepressants, are less frequently administered today. They function by raising the levels of norepinephrine, serotonin, and dopamine in the brain by inhibiting the action of an enzyme called monoamine oxidase. Marplan (isocarboxazid) and Nardil (phenelzine) are common MAOIs.
- Serotonin modulators. These medications increase the serotonin levels in the brain by blocking its reabsorption. Additionally, they also act on various postsynaptic serotonin receptors. Examples include Viibryd (vilazodone), trazodone, and nefazodone.
- Atypical antidepressants. Antidepressants classified as atypical do not belong to any of the four above-mentioned categories. These medications also increase neurotransmitter levels in the brain via various mechanisms. Examples are Remeron (mirtazapine) and Wellbutrin (bupropion).
When to Consider Antidepressants?
It is important to understand that antidepressants are not a cure for depression but can help alleviate symptoms and improve quality of life.
Here are some factors to consider when deciding whether prescribed depression medication might be appropriate for you:
- The severity of symptoms. Antidepressants could be a good treatment choice if you have moderate to severe depressive symptoms like significant impairment in everyday functioning or suicidal thoughts.
- Duration of symptoms. Antidepressant medication may be an option if your depressive symptoms have persisted for several weeks or months and are not getting better.
- History of depression. If you have a history of depression or have experienced several episodes, antidepressants may be used as a preventative treatment to lower the risk of subsequent episodes.
- Ineffectiveness of other treatments. If you have tried other treatments, such as therapy or lifestyle changes, and have not seen significant improvement, antidepressant pills may be worth considering.
The choice to get depression medication should ultimately be taken in collaboration with a healthcare provider. A mental health professional will conduct a psychiatric evaluation of your unique circumstances to suggest the best course of action.
Can You Get Antidepressants Without Seeing a Doctor?
It is neither legal nor safe to get anti-depression meds without a prescription from a licensed mental health professional, such as a doctor or psychiatrist. Antidepressants are prescription medications that require careful monitoring and management by a medical professional because they can cause side effects and can interact with other medications.
It is important to seek medical advice from a licensed healthcare provider before getting antidepressant prescriptions. They will assess your symptoms, medical history, and current medications to determine if antidepressants are an appropriate treatment option for you. During the course of treatment, they will monitor your progress and adjust your medication regimen to ensure the best possible outcome.
If you have symptoms of depression or other mental health problems, seeking professional help as soon as possible is important. A medical practitioner can provide an accurate diagnosis and develop a treatment plan that may include medications, therapy, and other interventions as appropriate.
How to Get Prescribed Antidepressants?
The first step to getting a prescription for antidepressants is to consult a health professional. They will evaluate your symptoms, medical history, and any other relevant factors to determine if antidepressants are an appropriate treatment option for you.
If your healthcare professional determines that antidepressants are appropriate for your condition, they will prescribe the suitable medication and discuss the potential benefits and risks.
Who Can Prescribe Antidepressants
In most cases, antidepressant medications can be prescribed by any of the following healthcare professionals:
- Psychiatrists. These are medical professionals with expertise in the identification and management of mental health issues, such as depression, anxiety, and others. They have the legal right to write prescriptions and provide psychotherapy.
- Primary care physicians. These medical professionals offer primary care and treatment for various conditions, including mental health disorders. If necessary, they can recommend patients to mental health professionals and write prescriptions for antidepressants.
- Nurse practitioners. These nurses are advanced practice professionals with additional education and training in identifying and managing mental health issues. Depending on their level of permission, they might prescribe antidepressants.
- Physician assistants. These are healthcare professionals who can perform duties including conducting physical examinations, diagnosing and treating medical conditions, interpreting diagnostic tests, and prescribing medications. They can prescribe antidepressants either under the supervision of a licensed physician or independently.
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How to Ask Your Doctor for Antidepressants?
It’s important to be open and honest with your doctor about your symptoms, worries, and treatment alternatives if you ask for depression medicines. Here is how to get antidepressants that will help you best:
- Schedule an appointment. To discuss your symptoms and possible treatments, make an appointment with your doctor. It could be beneficial to list your symptoms and any questions you have before the visit.
- Be honest about your symptoms. During the appointment, be honest and thoroughly detail your symptoms, how they affect your life, and any efforts you made to manage them.
- Discuss the treatment options. Your doctor may recommend various treatment options, including antidepressants, therapy, or lifestyle changes. Ask about the benefits of each option and how the newly prescribed medicines might interact with other medications or affect underlying health conditions.
- Express your preferences. Tell your doctor if you think you may benefit from antidepressant medication. Discuss your preferences and any apprehensions you may have about taking medication in clear terms. However, if the doctor determines that a different antidepressant may be more suitable for you, they will prescribe that instead.
- Follow your doctor’s recommendations. If your doctor agrees that antidepressants may be helpful, they will provide a prescription and instructions on how to take the medication. Follow their instructions carefully, and report any side effects or concerns.
Can Online Doctors Prescribe Depression Medication?
Yes, online doctors or telemedicine providers can prescribe antidepressants if certain regulations are met. Since antidepressants are not controlled substances, an in-person consultation with a physician may not be needed for their prescription online. In general, online prescribing of antidepressants may require the following:
- An initial online consultation. If you require an antidepressant prescription online, you’ll need to see a medical professional via telehealth technology. After carefully evaluating and diagnosing your condition, the doctor will determine the best course of treatment for you, which can include specific antidepressant medicines. You will also be able to request prescription refills during online consultations.
- Access to medical records. An online doctor or telemedicine provider may need access to your medical records to evaluate your condition, medical history and determine if medication for depression is an appropriate treatment option.
- Compliance with regulations. The same rules and regulations that apply to traditional in-person prescribing, such as those concerning prescription medications and informed consent, may also apply to online prescribing.
Risks and Side Effects of Antidepressants
While antidepressants can be effective in managing symptoms, there are potential
- Increased suicidal thoughts or behavior. Some
antidepressants [3*]may increase the risk of suicidal thoughts or behavior, particularly in children, adolescents, and young adults.
- Sexual dysfunction. Antidepressants can affect
sexual function [4*], causing decreased libido, difficulty achieving orgasm, and erectile dysfunction.
- Weight gain. Some antidepressants may cause
weight gain [5*], which can increase the risk of obesity and related health problems.
- Nausea and vomiting. Common side effects of many antidepressants include nausea and vomiting, which can be mild or severe.
- Insomnia. Antidepressants can cause insomnia or exacerbate existing
sleep problems [6*].
- Drowsiness. Some antidepressants can cause drowsiness, which can impair a person’s ability to perform daily activities.
- Dry mouth. Antidepressants can cause dry mouth, which can increase the risk of tooth decay and gum disease.
- Agitation and anxiety. In some cases, antidepressants can worsen agitation and anxiety, especially in people with bipolar disorder.
- Withdrawal symptoms. Stopping antidepressants abruptly can cause
withdrawal symptoms [7*]such as dizziness, nausea, headaches, and mood swings.
- Interactions with other medications. Drug interactions between antidepressants and other certain medications, including over-the-counter medicines and herbal supplements, can have harmful adverse effects.
Antidepressants may carry risks for
It is significant to remember that not everyone has these side effects, and some individuals may suffer other negative consequences not included in this list. Before beginning or quitting any medicine, speaking with a doctor and disclosing any side effects is imperative.
Alternative Depression Treatments
There are several alternative treatments for depression other than antidepressants. Here are some options:
- Therapy. Talk therapy, like cognitive-behavioral therapy (
CBT [9*]), can be highly effective in treating depression. Therapy can help you identify and change negative thinking and behavior patterns contributing to depression.
- Exercise. Exercising regularly has been
shown [10*]to be as effective as antidepressants in overcoming mild to moderate depression. It happens because exercise releases endorphins, which can boost your mood and reduce stress.
- Meditation and mindfulness. These
practices [11*]can help reduce stress and anxiety, which can improve symptoms of depression. They can also help you focus on the present moment and release negative thoughts.
- Acupuncture. This ancient Chinese practice involves inserting needles into specific points on the body to stimulate energy flow and promote healing. Some
studies [12*]suggest that acupuncture may be effective for depression.
- Herbal supplements. Some herbal supplements, such as
St. John’s wort [13*], may effectively treat mild to moderate depression. However, talking to your doctor before taking herbal supplements is important, as they can interact with other medications you may be taking.
It’s important to remember that while these alternative therapies may work for some people, they might not work for everyone. It’s wise to see your doctor before beginning any new ways to treat depression symptoms.
Remember that antidepressants can have adverse effects and may not work for everyone. However, speaking with a health professional for the best recommendation is essential if you need to take antidepressants. Additionally, follow up with your primary care physician or a psychiatrist on a regular basis to monitor your progress and modify your treatment plan as required.
Frequently Asked Questions
No, antidepressants are prescription medicines. Therefore, they must be prescribed, and the treatment course should be monitored by a prescriber, because these medicines may have side effects and interact with other medications.
You might not get prescribed antidepressants if the therapist decides on another course of depression treatment. You often have the option to decline medication suggestions and request an alternate treatment plan. However, discuss in detail your concerns with your doctor for the right decision.
The following over-the-counter (OTC) substances can be used for depression management:
- St. John's Wort
- Omega-3 Fatty Acids
- Rhodiola Rosea
- Vitamins and minerals
When it comes to specific pills like SSRIs, SNRIs, and other depression meds, they are available by prescription only.
Always discuss it with your doctor before using any OTC substances for depression.
A medical expert must determine that you have depression or another condition and that antidepressants can help treat its symptoms in order to write you an antidepressant prescription.
Taking antidepressants without depression can cause side effects. High levels of serotonin can lead to agitation or restlessness, and an excess of serotonin in the body may lead to serotonin syndrome.
- Antidepressants. (2023)
- Understanding Side Effects of Antidepressants: Large-scale Longitudinal Study on Social Media Data. (2021)
- Antidepressants and Suicide in Adolescents and Adults. (2009)
- Antidepressant-associated sexual dysfunction: impact, effects, and treatment. (2010)
- Antidepressant utilisation and incidence of weight gain during 10 years’ follow-up: population based cohort study. (2018)
- Antidepressants and their effect on sleep. (2005)
- Antidepressant Withdrawal and Rebound Phenomena. (2019)
- Antidepressants in pregnancy: a systematic review. (2010)
- Cognitive Behavioral Therapy for Depression. (2020)
- The Benefits of Exercise for the Clinically Depressed. (2004)
- Critical Analysis of the Efficacy of Meditation Therapies for Acute and Subacute Phase Treatment of Depressive Disorders: A Systematic Review. (2015)
- Acupuncture for depression. (2018)
- St John's Wort for Depression. (2000)